F-Actin (Smooth Muscle) Antibody, IgA : ARUP Lab Tests

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F-Actin (Smooth Muscle) Antibody, IgA : 0051724

Mnemonic: ACTIN IGA

Methodology:	Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed:	Tue
Reported:	1-8 days
Specimen Required:	Collect: Serum separator tube. Specimen Preparation: Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Storage/Transport Temperature: Refrigerated. Unacceptable Conditions: Plasma. Contaminated, severely hemolyzed, icteric, or lipemic specimens. Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval: 20.0 Units or less: Negative 20.1 - 24.9 Units: Equivocal 25.0 Units or greater: Positive
Interpretive Data:	The presence of IgA antibodies against F-Actin in patients having positive serologic markers for celiac disease, such as antiendomysial, anti-transglutaminase, and/or anti-gliadin peptide IgA, indicates the presence of intestinal villus atrophy. Positive results should be confirmed with biopsy.
CPT Code(s):	83516

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