ARUP's Laboratory Test Directory

Transplantation (ImmuKnow®) Immune Cell Function Assay : 0051272
[ image for: Time Sensitive]
Time Sensitive
  


Mnemonic: TICFA

Methodology: Cell Culture/Quantitative Chemiluminescence
Performed: Mon-Sun
Reported: 1-2 days
Specimen Required: Collect: Green (sodium heparin). Specimen must be collected within 30 hours of test performance.

Specimen Preparation: Transport 3 mL whole blood in original collection tube. (Min: 0.5 mL) LIVE LYMPHOCYTES REQUIRED.

Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE. Do not refrigerate or freeze.

Unacceptable Conditions: Frozen or refrigerated specimens. Specimens in transport longer than 30 hours.

Stability (collection to initiation of testing): Ambient: 30 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval:
226-524 ng/mL ATP
Interpretive Data: This assay quantifies the concentration of adenosine triphosphate (ATP) produced by circulating immune cells in response to phytohemagglutinin-L (PHA-L) stimulation. This assay does not directly quantify the level of immunosuppression.
 
ATP Level Result Interpretation Risk of Infection Risk of Rejection
225 ng/mL or lower Low The patient's circulating immune cells are showing low response to PHA stimulation. Increased Decreased
226-524 ng/mL Moderate The patient's circulating immune cells are showing moderate response to PHA stimulation. Normal Decreased
525 ng/mL or greater Strong The patient's circulating immune cells are showing strong response to PHA stimulation. Normal Increased

CPT Code(s): 86352
Cross References: ImmuKnow® Immune Cell Function Assay (Transplantation (ImmuKnow®) Immune Cell Function Assay) , Immune Cell Function Assay (Transplantation (ImmuKnow®) Immune Cell Function Assay)
 
 

 

 

 
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