Motor & Sensory Neuropathy Evaluation with Reflex to ANNA Titer & ANNA Immunoblot : ARUP Lab Tests

Testing Information

ARUP's Laboratory Test Directory

Motor & Sensory Neuropathy Evaluation with Reflex to ANNA Titer & ANNA Immunoblot : 0051224

Mnemonic: MSN EVAL

Methodology:	Refer to individual components
Performed:	Tue-Thu
Reported:	1-8 days
Specimen Required:	Collect: One 6 mL serum separator tube. Storage/Transport Temperature: 2 mL serum, frozen. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. Remarks: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Separate serum from cells ASAP. Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, icteric, ambient, or refrigerated specimens. Urine and other body fluids. Stability (collection to initiation of testing): Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year

Reference Interval:

Test Number	Components	Reference Interval
	Ganglioside (asialo-GM1) Antibody, IgG/IgM	29 IV or less: Negative 30-50 IV: Weak Positive 51-150 IV: Positive 151 IV or greater: Strong Positive
	Ganglioside (GM1) Antibody, IgG/IgM	29 IV or less: Negative 30 IV-50 IV: Weak Positive 51 IV-150 IV: Positive 151 IV or greater: Strong Positive
	Ganglioside (GD1a) Antibody, IgG/IgM	29 IV or less: Negative 30 IV-50 IV: Weak Positive 51 IV-150 IV: Positive 151 IV or greater: Strong Positive
	Ganglioside (GD1b) Antibody, IgG/IgM	29 IV or less: Negative 30 IV-50 IV: Weak Positive 51 IV-150 IV: Positive 151 IV or greater: Strong Positive
	Ganglioside (GQ1b) Antibody, IgG/IgM	29 IV or less: Negative 30 IV-50 IV: Weak Positive 51 IV-150 IV: Positive 151 IV or greater: Strong Positive
0051285	Myelin Associated Glycoprotein (MAG) Antibody, IgM	Less than 1000 TU
0051284	Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM	Less than 1.00 IV
	Neuronal Nuclear Antibody (ANNA) IgG Screen, by IFA	< 1:10
0050912	Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum	< 1:10 No antibody detected.
	Neuronal Nuclear Antibody IgG, Immunoblot Anti-Hu	Negative
	Neuronal Nuclear Antibody IgG, Immunoblot Anti-Ri	Negative

Note:

ANNA antibodies are screened by IFA. If the IFA screen is 1:10, then a titer and immunoblot (Hu and Ri) will be added.

CPT Code(s):

83516 x5 Asialo-GM1; 83516 MAG IgM ELISA; 83516 SGPG IgM
86255 ANNA; if reflexed, add 86256 ANNA titer and 83516 Immunoblot