ARUP's Laboratory Test Directory

0051224: Motor & Sensory Neuropathy Evaluation with Reflex to ANNA Titer & ANNA Immunoblot

Test Mnemonic: MSN EVAL
Methodology: Refer to individual components

Performed: Tue-Thu

Reported: 1-8 days

Specimen Required:  
Collect: One 6 mL SST.

Transport: 2 mL serum, frozen. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 1 mL serum, frozen.

Remarks: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Separate serum from cells ASAP.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, icteric, ambient, or refrigerated specimens. Urine and other body fluids.

Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year

Reference Interval:
 
Test Number Components Reference Interval
 Ganglioside (asialo-GM1) Antibody, IgG/IgM 29 IV or less: Negative
30-50 IV: Weak Positive
51-150 IV: Positive
151 IV or greater: Strong Positive
 Ganglioside (GM1) Antibody, IgG/IgM 29 IV or less: Negative
30 IV-50 IV: Weak Positive
51 IV-150 IV: Positive
151 IV or greater: Strong Positive
 Ganglioside (GD1a) Antibody, IgG/IgM 29 IV or less: Negative
30 IV-50 IV: Weak Positive
51 IV-150 IV: Positive
151 IV or greater: Strong Positive
 Ganglioside (GD1b) Antibody, IgG/IgM 29 IV or less: Negative
30 IV-50 IV: Weak Positive
51 IV-150 IV: Positive
151 IV or greater: Strong Positive
 Ganglioside (GQ1b) Antibody, IgG/IgM 29 IV or less: Negative
30 IV-50 IV: Weak Positive
51 IV-150 IV: Positive
151 IV or greater: Strong Positive
0051285Myelin Associated Glycoprotein (MAG) Antibody, IgM Less than 1000 TU
0051284Sulfate-3-Glucuronyl Paragloboside (SGPG) Antibody, IgM Less than 1.00 IV
 Neuronal Nuclear Antibody (ANNA) IgG Screen, by IFA < 1:10
0050912Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum < 1:10 No antibody detected.
 Neuronal Nuclear Antibody IgG, Immunoblot Anti-Hu Negative
 Neuronal Nuclear Antibody IgG, Immunoblot Anti-Ri Negative

Note:
ANNA antibodies are screened by IFA. If the IFA screen is 1:10, then a titer and immunoblot (Hu and Ri) will be added.

CPT Code(s):
83516 x5 Asialo-GM1; 83516 MAG IgM ELISA; 83516 SGPG IgM
86255 ANNA; if reflexed, add 86256 ANNA titer and 83516 Immunoblot

 

 

 
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