ARUP's Laboratory Test Directory

Cardiolipin Antibodies, IgG, IgM, and IgA : 0051162

Mnemonic: CARD PAN

Ordering Recommendation: Not a recommended panel for the diagnosis of antiphospholipid syndrome (APS). The combined IgG and IgM cardiolipin (aCL) test (0099344) is preferred.
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
 
Test Number Components Reference Interval
0050901Cardiolipin Antibody, IgG 0-14 GPL: Negative
15-19 GPL: Indeterminate
20-80 GPL: Low to Medium positive
81 GPL or above: High positive
0050902Cardiolipin Antibody, IgM 0-12 MPL: Negative
13-19 MPL: Indeterminate
20-80 MPL: Low to Medium Positive
81 MPL or above: High positive
0098358Cardiolipin Antibody, IgA 0-11 APL: Negative
12-19 APL: Indeterminate
20-80 APL: Low to Medium positive
81 APL or above: High Positive

CPT Code(s): 86147 x3
Cross References: aCL Antibodies (Cardiolipin Antibodies, IgG, IgM, & IgA)