ARUP's Laboratory Test Directory

Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA : 0051044

Mnemonic: C6 PEP

Ordering Recommendation: First-line serologic screening test for suspected Lyme disease. Positive or equivocal results must be confirmed with a Western blot.
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Tue
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
0.90 LI or less:  Negative - C6 peptide antibody to B. burgdorferi not detected.
0.91 - 1.09 LI:  Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 LI or greater: Positive - C6 peptide antibody to B. burgdorferi detected.
Interpretive Data: LI - Lyme Index
CPT Code(s): 86618
Cross References: Borrelia afzeli (Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA) , Borrelia garinii (Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA) , Lyme Disease (Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA)