ARUP's Laboratory Test Directory

Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG & IgM by Western Blot : 0051043

Mnemonic: C6 ACUTE R

Ordering Recommendation: Preferred reflex test to detect Lyme disease in individuals with ≤4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by Western blot.
Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Western Blot
Performed: Tue
Reported: 1-9 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
 
Test Number Components Reference Interval
0051044Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA 0.90 LI or less:  Negative - C6 peptide antibody to B. burgdorferi not detected.
0.91 - 1.09 LI:  Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 LI or greater: Positive - C6 peptide antibody to B. burgdorferi detected.
0050255Borrelia burgdorferi Antibody, IgG by Western Blot Effective August 15, 2011

Negative
0050253Borrelia burgdorferi Antibody, IgM by Western Blot Effective August 15, 2011

Negative

Interpretive Data: Refer to report.
Note: If C6 Peptide by ELISA is 0.91 LI or greater, then IgG and IgM Western blot will be added. Additional charges apply.
CPT Code(s): 86618; if positive add; 86617 x2
Cross References: Lyme Disease (Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG & IgM by Western Blot) , VlsE Lipoprotein (Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG & IgM by Western Blot)