Reference Interval:
Negative: 19 AU/mL or less
Equivocal: 20-25 AU/mL
Positive: 26 AU/mL or greater
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| Interpretive Data: |
The presence of anti-glomerular basement membrane (GBM) antibodies by multi-analyte fluorescent detection (MAFD) may aid in the diagnosis of Goodpasutre syndrome. False positive results may occur due to reactivity against other chains of type IV collagen. If MAFD is negative but there is strong suspicion for disease, renal biopsy may be indicated. A renal biopsy may also be essential in suspected Goodpasture disease with renal involovement, allowing diagnostic confirmation and assesssment of renal prognosis.
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| CPT Code(s): |
83516
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Cross References: |
Anti-GBM Antibody, IgG (ELISA), Anti-Glomerular Basement Membrane Antibody, IgG (ELISA) |