ARUP's Laboratory Test Directory
| 0050912: Neuronal Nuclear Antibody (ANNA) Titer IgG by IFA, Serum |
| Test Mnemonic: ANNAGIFA | |
|
Methodology: Indirect Fluorescent Antibody
Performed: Wed Reported: 1-9 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum, frozen. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum, frozen. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
|
| Reference Interval: |
| < 1:10 No antibody detected. |
| Interpretive Data: | |
|
A titer of greater than or equal to 1:10 indicates antibody was detected to either ANNA-1 (anti-Hu) or ANNA-2 (anti-Ri). An immunoblot assay should be completed for confirmation of ANNA-1 or ANNA-2.
Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
| Titers of greater than or equal to 1:10 indicate antibody was detected to either ANNA-1 (anti-Hu) or ANNA-2 (anti-Ri) and will be titered to endpoint. This test is used primarily for titering patient sera that have previously been confirmed as positive for either ANNA-1 or ANNA-2 by immunoblot. Only an immunoblot can differentiate between ANNA-1 and ANNA-2. |
| CPT Code(s): | |
| 86256 |