ARUP's Laboratory Test Directory

0050902: Cardiolipin Antibody, IgM

Test Mnemonic: AC-IGM
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun-Sat

Reported: 1-2 days

Specimen Required:  
Collect: One 4 mL SST. 

Transport: 1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.15 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.

Unacceptable Conditions: Plasma and other body fluids.  Heat-inactivated, hemolyzed, lipemic, or contaminated specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
< 12 MPL: Absent or none detected
12-19 MPL: Inconclusive
20-79 MPL: Moderate positive
³ 80 MPL: High positive

Interpretive Data:
Results in the inconclusive range and positive results for IgM only should be carefully interpreted.  Most patients with "antiphospholipid antibody syndrome" (Br J Rheumatol 26:324-326, 1987) have moderate or high levels of cardiolipin antibodies and are positive for IgG only or IgG and IgM.



Note:
MPL = IgM phospholipid units

CPT Code(s):
86147

 

 

 
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