ARUP's Laboratory Test Directory

Cardiolipin Antibody, IgM : 0050902

Mnemonic: AC-IGM

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  One 4 mL serum separator tube. 

Storage/Transport Temperature:  1 mL serum at 2-8°C.  (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Plasma and other body fluids.  Heat-inactivated, hemolyzed, lipemic, or contaminated specimens.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
< 12 MPL: Absent or none detected
12-19 MPL: Inconclusive
20-79 MPL: Moderate positive
≥ 80 MPL: High positive
Interpretive Data: Most patients with antiphospholipid antibody syndrome (APS) have medium or high levels of anticardiolipin IgG and/or IgM antibodies. All positive results should be retested on two or more occasions and at least 12 weeks apart to confirm persistence (J Thromb Haemost. 2006;4:295-306).
Note: MPL = IgM phospholipid units
CPT Code(s): 86147
Cross References: Anti-Cardiolipin Antibody, IgM, Anti-Phospholipid Antibody, IgM, Phospholipid Antibody, IgM
 
 

 

 

 
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