ARUP's Laboratory Test Directory

Cardiolipin Antibody, IgM : 0050902

Mnemonic: AC-IGM

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  One 4 mL serum separator tube. 

Transport:  1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.15 mL serum at 2-8°C.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Plasma and other body fluids.  Heat-inactivated, hemolyzed, lipemic, or contaminated specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
< 12 MPL: Absent or none detected
12-19 MPL: Inconclusive
20-79 MPL: Moderate positive
³ 80 MPL: High positive
Interpretive Data: Results in the inconclusive range and positive results for IgM only should be carefully interpreted.  Most patients with "antiphospholipid antibody syndrome" (Br J Rheumatol 26:324-326, 1987) have moderate or high levels of cardiolipin antibodies and are positive for IgG only or IgG and IgM.
Note: MPL = IgM phospholipid units
CPT Code(s): 86147
 
 

 

 

 
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