ARUP's Laboratory Test Directory
| 0050807: Bordetella pertussis Antibodies, IgA & IgG |
| Test Mnemonic: BORD PAN2 | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Tue Reported: 1-8 days |
| Specimen Required: | |
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Collect: One 4 mL SST. Transport unprocessed specimens ASAP or according to stability guidelines.
Transport: 1 mL serum at 2-8°C. (Min: 0.3 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.1 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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8 Units or less: Negative - No significant level of detectable Bordetella pertussis antibody. 9-11 Units: Equivocal - Repeat testing in 10-14 days may be helpful. 12 Units or greater: Positive - Antibody to Bordetella pertussis detected which may indicate a current or past exposure/immunization to B. pertussis. |
| Interpretive Data: | |
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Detectable levels of IgG antibodies to B. pertussis may be seen in the serum of vaccinated individuals of all ages, in early infancy as the result of placental transfer, and in the convalescent phase of a recent infection. IgG antibodies can only be used to diagnose active infection when paired sera are available and a rise in antibody level can be demonstrated. A significant rise may not always be demonstrated as peak levels of IgG may be reached before the first sample is collected. Therefore, IgA and IgM antibody levels should be measured to diagnose active disease.
Please refer to Statement A in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 86615 x2 Bordetella IgA and IgG |