ARUP's Laboratory Test Directory
| 0050777: Treponema pallidum Antibody by TP-PA |
| Test Mnemonic: MHA | |
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#ExistMethodology>
Methodology: Indirect Hemagglutination
*ExistMethodology> #ExistPerformed> Performed: Mon-Fri *ExistPerformed> #ExistReported> Reported: 1-4 days *ExistReported> |
| Specimen Required: | |
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#ExistCollect>
Collect: One 4 mL SST or PST.
*ExistCollect> #ExistTransport> Transport: 1 mL serum or plasma at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistPedCollectTransport> Pediatric Collection/Transport: 0.15 mL serum or plasma at 2-8°C. *ExistPedCollectTransport> #ExistRemarks> Remarks: Separate serum or plasma from cells ASAP. *ExistRemarks> #ExistConditions> Unacceptable Conditions: CSF or other body fluids. *ExistConditions> #ExistStability> Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) *ExistStability> |
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| Reference Interval: |
| #ExistRefRange> Nonreactive *ExistRefRange> |
| Note: | |
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TP-PA is a helpful diagnostic aid for the patient with a reactive reagin test, but presents with atypical signs of primary, secondary, or late syphilis. TP-PA compares favorably with the FTA test, but appears slightly less sensitive in cases of untreated early primary syphilis. In late syphilis, the agreement with FTA is 99%. VDRL is the preferred test for cerebrospinal fluid. Treponemal tests (TP-PA or FTA) are not recommended for CSF. FTAs on CSF may be tested, but TP-PA cannot be tested on CSF. |
| CPT Code(s): | |
| 86781 |