ARUP's Laboratory Test Directory

Mycoplasma pneumoniae Antibodies Seroconversion Panel, IgG & IgM : 0050697

Mnemonic: MYCO SERO

Methodology: Semi-Quantitative Enzyme Immunoassay
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Serum separator tube (acute) AND serum separator tube (convalescent).

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum (acute) AND 0.5 mL serum (convalescent) to individual ARUP Standard Transport Tubes. (Min: 0.1 mL each) Mark specimens clearly as "acute" or "convalescent" with appropriate draw dates. If acute specimen was previously tested by ARUP, convalescent specimen must be submitted within 30 days if seroconversion comparison testing is desired.

Storage/Transport Temperature: Refrigerated.

Remarks: Testing will not be performed unless both acute and convalescent specimens are available.

Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
 
Test Number Components Reference Interval
0050397Mycoplasma pneumoniae Antibody, IgG < 0.10 U/L: Negative
0.10-0.32 U/L: Equivocal
> 0.32 U/L: Positive
0050398Mycoplasma pneumoniae Antibody, IgM 0.76 U/L or less: Negative - No clinically significant amount of M. pneumoniae IgM antibody detected.
0.77-0.95 U/L: Low Positive - M. pneumoniae-specific IgM presumptively detected.  Collection of a follow-up sample in one to two weeks is recommended to assure reactivity.
0.96 U/L or greater: Positive - Highly significant amount of M. pneumoniae-specific IgM antibody detected.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
 
Note: If both Mycoplasma pneumoniae IgG values are above 0.32 U/L, a ratio will be calculated and the significance will be noted on the report.
CPT Code(s): 86738 x4
Cross References: Atypical Pneumonia (Mycoplasma pneumoniae Antibodies Seroconversion Panel, IgG & IgM) , Mycoplasma G/M Ab Seroconversion (Mycoplasma pneumoniae Antibodies Seroconversion Panel, IgG & IgM) , Walking Pneumonia (Mycoplasma pneumoniae Antibodies Seroconversion Panel, IgG & IgM)