ARUP's Laboratory Test Directory

Extractable Nuclear Antigen Antibodies (RNP, Smith, Scleroderma, SSA, & SSB) : 0050653

Mnemonic: ENA ABS5

Methodology: Semi-Quantitative Multiplex Bead Assay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma or other body fluids. Bacterially contaminated or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
Test Number Components Reference Interval
0050470RNP (U1) (Ribonucleic Protein) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
 Smith (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050691SSA (Ro) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050692SSB (La) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050599Scleroderma (Scl-70) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
 
CPT Code(s): 86235 x5
Cross References: Anti-ENA Antibodies (Extractable Nuclear Antigen Antibodies (RNP, Smith, Scleroderma, SSA, & SSB)), Connective Tissue Disease (Extractable Nuclear Antigen Antibodies (RNP, Smith, Scleroderma, SSA, & SSB))