Bence Jones Protein, Quantitative Free Kappa & Lambda Light Chains, Urine : ARUP Lab Tests

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Bence Jones Protein, Quantitative Free Kappa & Lambda Light Chains, Urine : 0050618

Mnemonic: BJ QUANT

Methodology:	Immunofixation Electrophoresis/Nephelometry
Performed:	Mon-Fri
Reported:	1-5 days
Specimen Required:	Patient Prep: 24-hour Urine, refrigerated during collection. Collect: 24-hour urine. Urine supernate is also acceptable. Specimen needs to be refrigerated during collection. Storage/Transport Temperature: Two 4.5 mL aliquots from a well-mixed 24-hour collection at 2-8°C. (Min: 3.0 mL) Submit specimen in two ARUP Standard Transport Tubes. Remarks: Keep refrigerated at all times. Record total volume and collection time interval on transport tube and test request form. Random urine specimens are acceptable, but not preferred. Unacceptable Conditions: Specimens that are not refrigerated. Stability (collection to initiation of testing): Ambient: 2 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval:

Test Number	Components	Reference Interval
	Total Protein	10-140 mg/d
	Albumin, Urine	Detected
	Alpha-1 Globulins, Urine	None detected
	Alpha-2 Globulins, Urine	None detected
	Beta Globulins, Urine	None detected
	Gamma, Urine	None detected
	Free Urinary Kappa Light Chains	0.14 - 2.42 mg/dL
	Free Urinary Kappa Excretion/Day	By report
	Free Urinary Lambda Light Chain	0.02 - 0.67 mg/dL
	Free Urinary Lambda Excretion/Day	By report
	Free Urinary Kappa/Lambda Ratio	2.04 - 10.37 (ratio)
	IFE Interpretation	By report

Interpretive Data:

Total urinary protein is determined nephelometrically by adding the albumin and kappa and/or lambda light chains. This value may not agree with the total protein as determined by chemical methods, which characteristically underestimate urinary light chains.

CPT Code(s):

84156 Total protein; 86335 IFE; 83883 x2 Nephelometry, kappa/lambda

Cross References:

Electrophoresis, Protein, Urine, Free Kappa & Lambda Light Chains (Bence Jones Protein), Urine by Immunofixation Electrophoresis, Qua, Immunofixation Electrophoresis, Urine, Protein Electrophoresis, Urine

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