|25.0 Units or
#ExistInterpData>In the context of vitamin B12 deficiency, the presence of gastric parietal cell antibodies (PCA) and/or intrinsic factor antibodies in association with macrocytic anemia is considered diagnostic for pernicious anemia (PA). However, the presence of gastric PCAs alone is not specific for PA. Gastric PCAs may occur with increased frequency in unaffected family members, a small percentage of healthy individuals, and patients with other autoimmune diseases, such as autoimmune thyroiditis.
||Most patients with pernicious anemia have parietal cell antibodies. However, the fact that such antibodies are found with increased frequency in unaffected family members, as well as in patients with other autoimmune diseases, suggests these antibodies do not cause disease by themselves.
||Anti-GPA (AGPA) (Gastric Parietal Cell Antibody, IgG), Anti-Gastric Parietal Cell Antibody (AGPCA) (Gastric Parietal Cell Antibody, IgG)
, Hydrogen Potassium (H+/K+) ATPase (Gastric Parietal Cell Antibody, IgG), Pernicious Anemia (Gastric Parietal Cell Antibody, IgG)