ARUP's Laboratory Test Directory
| 0050567: Inflammatory Bowel Disease Differentiation Profile |
| Test Mnemonic: IBD | |
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Methodology: Enzyme-Linked Immunosorbent Assay/Indirect Fluorescent Antibody
Performed: Refer to individual components Reported: Refer to individual components |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1.5 mL serum at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.5 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: | |||||||||||||||
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| Interpretive Data: | |
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P-ANCA antibodies are found in 50-70% of ulcerative colitis (UC) patients, but in only 20% of Crohn disease (CD) patients. In contrast, Saccharomyces cerevisiae IgG antibodies are found in 80% of CD patients, but only 20% of UC patients. Saccharomyces cerevisiae IgA antibodies are found in 35% of CD patients but < 1% in UC patients.
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| Note: | |
| This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease. |
| CPT Code(s): | |
| 86671 x2 Semiquantitative immunoassay-fungus not elsewhere specified; 86255 Fluorescent noninfectious agent antibody screen |