ARUP's Laboratory Test Directory

Saccharomyces cerevisiae Antibodies, IgG & IgA : 0050564

Mnemonic: SC PAN

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue, Thu
Reported: 1-4 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Storage/Transport Temperature:  1 mL serum at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
Available Separately Components Reference Interval
No Saccharomyces cerevisiae Antibody, IgA 20.0 Units or less: Negative
20.1 to 24.9 Units: Equivocal
25.0 Units or greater: Positive
No Saccharomyces cerevisiae Antibody, IgG 20.0 Units or less: Negative
20.1 to 24.9 Units: Equivocal
25.0 Units or greater: Positive

Interpretive Data: Saccharomyces cerevisiae IgG antibodies are found in 60-70% of Crohn disease (CD) patients and 10-15% of ulcerative colitis (UC) patients. Saccharomyces cerevisiae IgA antibodies are found in about 35% of CD patients but less than 1% in UC patients. Detection of both Saccharomyces IgG and IgA antibodies in the same serum specimen is highly specific for CD.
Note: This test may be a useful tool for distinguishing ulcerative colitis (UC) from Crohn disease (CD) in patients with suspected inflammatory bowel disease.
CPT Code(s): 86671 x2
Cross References: IBD Antibodies, IgG & IgA
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org