ARUP's Laboratory Test Directory
| 0050553: Cytomegalovirus Antibody, IgM |
| Test Mnemonic: CMV IGM | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue-Sat Reported: 1-2 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.2 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.1 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent." Unacceptable Conditions: Severely lipemic, icteric, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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0.89 IV or less: Negative - No significant level of detectable CMV IgM antibody. 0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Positive - IgM antibody to CMV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
| Interpretive Data: | |
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In immunocompromised patients, CMV serology (IgG or IgM antibody titers) may not be reliable and may be misleading in the diagnosis of acute or reactivation CMV disease. The preferred method for diagnosis is culture of virus and/or demonstration of viral antigen in peripheral white cells (buffy coat), bronchoalveolar lavage (BAL) cells, or tissue biopsies.
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| CPT Code(s): | |
| 86645 |