ARUP's Laboratory Test Directory

Haemophilus influenzae b Antibody, IgG : 0050542

Mnemonic: HIBE IGG

Methodology: Quantitative Multi-Analyte Fluorescent Detection
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Serum separator tube. "Pre" and 30-day "post" Haemophilus influenzae b vaccination specimens should be submitted together for testing. "Post" specimen should be drawn 30 days after immunization and must be received within 60 days of "pre" specimen.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine".

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed or, severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
< 1.0 µg/mL = Antibody concentration not protective.
≥ 1.0 µg/mL = Antibody to H. influenzae b detected. Suggestive of protection.
Interpretive Data: Responder status is determined according to the ratio of post-vaccination concentration to pre-vaccination concentration of Haemophilus influenza b antibody, IgG as follows:
1.  If the post-vaccination concentration is less than 3.0 µg/mL, the patient is considered to be a nonresponder.
2.  If the post-vaccination concentration is greater than or equal to 3.0 µg/mL, a patient with a ratio of greater than or equal to 4 is a good responder, a ratio of 2-4 is a weak responder, and a ratio of less than 2 is considered a nonresponder.
CPT Code(s): 86317
Cross References: Haemophilus influenzae b Vaccine Response (Haemophilus influenzae b Antibody, IgG) , Vaccine Response (Haemophilus influenzae b Antibody, IgG)
 
 

 

 

 
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