ARUP's Laboratory Test Directory

Hemoglobin S, Evaluation with Reflex to RBC Solubility : 0050520

Mnemonic: SCKL

Methodology: High Performance Liquid Chromatography
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation: Transport 5 mL whole blood. (Min: 0.2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Frozen or room temperature specimens.

Stability (collection to initiation of testing): Ambient: Unacceptable, Refrigerated: 1 week, Frozen: Unacceptable
Reference Interval:
Negative
Note: If HPLC detects a peak which suggests Hgb S, then RBC Solubility will be added for confirmation. Additional charges apply.
CPT Code(s): 83021 Chromatography; if reflexed, add 85660 Sickling of RBC, reduction
Cross References: Sickle Cell Anemia Screen (Hemoglobin S, Evaluation with Reflex to RBC Solubility), Sickle Cell Disease (Hemoglobin S, Evaluation with Reflex to RBC Solubility), Sickle Cell Screen (Hemoglobin S, Evaluation with Reflex to RBC Solubility)