ARUP's Laboratory Test Directory

0050494: Interleukin 1 Beta by Chemiluminescence

Test Mnemonic: IL1B
Methodology: Chemiluminescent Immunoassay

Performed: Mon, Wed, Fri

Reported: 1-3 days

Specimen Required:  
Collect: One 3 mL plain red, lavender (EDTA), pink (K2EDTA), green (sodium or lithium heparin), amniotic fluid, or cell-free tissue culture supernatant.

Transport: 1 mL serum, plasma, amniotic fluid, or cell-free tissue culture supernatant, frozen. (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.3 mL serum, plasma, amniotic fluid, or cell-free tissue culture supernatant, frozen.

Remarks: CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered.  Separate serum, plasma, or fluid within 30 minutes from cells and freeze.  Avoid freeze/thaw cycles.

Unacceptable Conditions: Heat-inactivated, refrigerated or contaminated specimens.

Stability: After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year

Reference Interval:
< 5.0 pg/mL

Interpretive Data:


Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory.



Note:
Interleukin 1 beta mediates a wide variety of biological actions.  It stimulates the production and secretion of interleukin 2 and the expression of interleukin 2 receptors. In synergy with tumor necrosis factor alpha, elevated interleukin 1 beta levels are seen in septic shock as well as in the cerebrospinal fluid of meningitis and other central nervous system processes such as multiple sclerosis.

CPT Code(s):
82397

 

 

 
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