ARUP's Laboratory Test Directory

Rapid Plasma Reagin (RPR) with Reflex to Titer and TP-PA Confirmation : 0050478

Mnemonic: RPR PAN

Ordering Recommendation: CDC recommended test for the screening and diagnosis of syphilis. For RPR test that follows reverse algorithm, refer to Rapid Plasma Reagin (RPR) with Reflex to RPR Titer or T. pallidum Antibody by Particle Agglutination (2007443).
Methodology: Semi-Quantitative Charcoal Agglutination/Semi-Quantitative Particle Agglutination
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL) Do not freeze. Also acceptable: Plasma, if testing is completed within 48 hours of collection.

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: CSF or other body fluids.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
Test Number Components Reference Interval
 Rapid Plasma Reagin (RPR) Effective May 21, 2012
RPR (+) = Reactive
RPR (-) = Nonreactive
 Rapid Plasma Reagin (RPR) Titer < 1:1
 Treponema pallidum Antibody by TP-PA Nonreactive

Note: This panel is for clients in states where automatic confirmation using a treponemal test is required for all reactive RPR tests.

If RPR is reactive, then a titer to endpoint and TP-PA confirmation will be added. Additional charges apply.
CPT Code(s): 86592; if reflexed, add 86593 and 86780
Cross References: Rapid Plamsa Reagin (RPR) with MHA-TP Confirmation, Rapid Plasma Reagin (RPR) with MHA-TP Confirmation, RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing (Treponema pallidum (Rapid Plasma Reagin) with Reflex to Titer & TP-PA Confirmation) , Treponema pallidum (Rapid Plasma Reagin) with Reflex to Titer and TP-PA Confirmation