Reference Interval:
| Test Number
| Components
| Reference Interval
| | 0050381 | Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA
| < 1:64 Negative - No significant level of Rickettsia typhi IgG antibody detected.
1:64-1:128 Equivocal - Questionable presence of Rickettsia typhi IgG antibody detected. Repeat testing in 10-14 days may be helpful.
³ 1:256 Positive - Presence of IgG antibody to Rickettsia typhi detected, suggestive of current or past infection.
| | 0050383 | Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA
| < 1:64 Negative - No significant level of Rickettsia typhi IgM antibody detected.
³1:64 Positive - Presence of IgM antibody to Rickettsia typhi detected, suggestive of recent infection.
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| Interpretive Data: |
These tests are for antibodies to Rickettsia typhi. Any antibody reactivity to Rickettsia typhi antigen should, however, also be considered group-reactive for the Typhus Fever group (Rickettsia prowazekii). Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
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| CPT Code(s): |
86757 Typhus fever IgG; 86757 Typhus fever IgM
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