ARUP's Laboratory Test Directory

0050381: Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA

Test Mnemonic: TYPHU G
Methodology: Indirect Fluorescent Antibody

Performed: Tue, Fri

Reported: 1-5 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.15 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.  Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent."

Unacceptable Conditions: Severely lipemic, hemolyzed, or contaminated specimens.

Stability: After separation from cells:Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
< 1:64  Negative - No significant level of Rickettsia typhi IgG antibody detected.
1:64-1:128  Equivocal - Questionable presence of Rickettsia typhi IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
³ 1:256  Positive - Presence of IgG antibody to Rickettsia typhi detected, suggestive of current or past infection.

Interpretive Data:
This test is for antibodies to Rickettsia typhi.  Any antibody reactivity to Rickettsia typhi antigen should, however, also be considered group-reactive for the Typhus Fever group (Rickettsia prowazekii). Seroconversion between acute and convalescent sera is considered strong evidence of recent infection.  The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.



CPT Code(s):
86757

 

 

 
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