ARUP's Laboratory Test Directory
| 0050381: Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA |
| Test Mnemonic: TYPHU G | |
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#ExistMethodology>
Methodology: Indirect Fluorescent Antibody
*ExistMethodology> #ExistPerformed> Performed: Tue, Fri *ExistPerformed> #ExistReported> Reported: 1-5 days *ExistReported> |
| Specimen Required: | |
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#ExistCollect>
Collect: One 4 mL SST.
*ExistCollect> #ExistTransport> Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistPedCollectTransport> Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. *ExistPedCollectTransport> #ExistRemarks> Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimens plainly as "acute" or "convalescent." *ExistRemarks> #ExistConditions> Unacceptable Conditions: Severely lipemic, hemolyzed, or contaminated specimens. *ExistConditions> #ExistStability> Stability: After separation from cells:Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) *ExistStability> |
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| Reference Interval: |
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#ExistRefRange> < 1:64 Negative - No significant level of Rickettsia typhi IgG antibody detected. 1:64-1:128 Equivocal - Questionable presence of Rickettsia typhi IgG antibody detected. Repeat testing in 10-14 days may be helpful. ³ 1:256 Positive - Presence of IgG antibody to Rickettsia typhi detected, suggestive of current or past infection. *ExistRefRange> |
| Interpretive Data: | |
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#ExistInterpData>
This test is for antibodies to Rickettsia typhi. Any antibody reactivity to Rickettsia typhi antigen should, however, also be considered group-reactive for the Typhus Fever group (Rickettsia prowazekii). Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change (fourfold difference in titer) on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
*ExistInterpData> |
| CPT Code(s): | |
| 86757 |