ARUP's Laboratory Test Directory

Lysozyme, Serum or Body Fluid : 0050367

Mnemonic: LYSO

Methodology: Quantitative Radial Immunodiffusion
Performed: Mon-Fri
Reported: 1-5 days
Specimen Required: Collect: Serum separator tube, CSF, tears, or other body fluid. (Urine not accepted.)

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum OR 0.5 mL CSF, tears OR other body fluid to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Storage/Transport Temperature: Refrigerated.

Remarks: Indicate source on the test request form.

Unacceptable Conditions: Urine.

Stability (collection to initiation of testing): After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months
Reference Interval:
9-17 µg/mL
Interpretive Data:

See Compliance Statement D: www.aruplab.com/CS
Note: Serum and urine lysozyme levels may be elevated in acute myelomonocytic leukemia (FAB-M4), chronic myelomonocytic leukemia (CMML), and chronic myelocytic leukemia (CML). Increased serum lysozyme activity is present in tuberculosis, sarcoidosis, megaloblastic anemias, acute bacterial infections, ulcerative colitis, regional enteritis, and Crohn disease. Elevated levels of urine and serum lysozyme occur during severe renal insufficiency, renal transplant rejection, urinary tract infections, pyelonephritis, glomerulonephritis, and nephrosis.
CPT Code(s): 85549
Cross References: Muramidase (Lysozyme, Serum or Body Fluid)