ARUP's Laboratory Test Directory
| 0050367: Lysozyme, Serum or Body Fluid |
| Test Mnemonic: LYSO | |
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Methodology: Radial Immunodiffusion
Performed: Mon-Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: One 4 mL SST, CSF, tears, or other body fluid with the exception of urine.
Transport: 1 mL serum, 0.5 mL CSF, tears, or other body fluid in a leak-proof container at 2-8°C. Indicate source on the test request form. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum, 0.10 mL CSF, tears, or other body fluid in a leak-proof container at 2-8°C. Indicate source on the test request form. Remarks: Separate serum from cells ASAP and refrigerate. Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months |
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| Reference Interval: |
| 9-17 µg/mL |
| Interpretive Data: | |
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Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
| Serum and urine lysozyme levels may be elevated in acute myelomonocytic leukemia (FAB-M4), chronic myelomonocytic leukemia (CMML), and chronic myelocytic leukemia (CML). Increased serum lysozyme activity is present in tuberculosis, sarcoidosis, megaloblastic anemias, acute bacterial infections, ulcerative colitis, regional enteritis, and Crohn disease. Elevated levels of urine and serum lysozyme occur during severe renal insufficiency, renal transplant rejection, urinary tract infections, pyelonephritis, glomerulonephritis, and nephrosis. |
| CPT Code(s): | |
| 85549 |