ARUP's Laboratory Test Directory
| 0050365: Legionella pneumophila Antibody (Types 1-6), IgG by IFA |
| Test Mnemonic: LEGAB | |
|
#ExistMethodology>
Methodology: Indirect Fluorescent Antibody
*ExistMethodology> #ExistPerformed> Performed: Mon-Fri *ExistPerformed> #ExistReported> Reported: 1-4 days *ExistReported> |
| Specimen Required: | |
|
#ExistCollect>
Collect: One 4 mL SST.
*ExistCollect> #ExistTransport> Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistPedCollectTransport> Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. *ExistPedCollectTransport> #ExistRemarks> Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent." *ExistRemarks> #ExistConditions> Unacceptable Conditions: Severely lipemic, contaminated, or hemolyzed specimens. *ExistConditions> #ExistStability> Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) *ExistStability> |
|
| Reference Interval: |
|
#ExistRefRange> <1:128 Negative - No significant level of Legionella pneumophila Type 1-6 IgG antibody detected. 1:128 Equivocal - Questionable presence of Legionella pneumophila Type 1-6 IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1:256 or greater Positive - Presence of Legionella pneumophila Type 1-6 IgG antibody detected, suggestive of current or past infection. *ExistRefRange> |
| Interpretive Data: | |
|
#ExistInterpData>
Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time. This assay may detect infection by any of the serotypes 1-6. The CDC and many state health laboratories recommend testing only for antibody to Legionella pneumophila Type 1. For equivocal or positive IFA results, the CDC protocol suggests follow-up testing for Legionella pneumophila antibody Type 1.
*ExistInterpData> |
| Note: | |
| For follow-up testing on equivocal or positive results, refer to Legionella pneumophila Antibody (Type 1), IgG by IFA (0050376). |
| CPT Code(s): | |
| 86713 |