Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®), CSF
:0050359
Mnemonic: HERPIICSF
Methodology:
Enzyme-Linked Immunosorbent Assay
Performed:
Sun, Tue-Sat
Reported:
1-2 days
Specimen Required:
Collect: CSF.
Storage/Transport Temperature: 0.5 mL CSF at 2-8°C. (Min: 0.2 mL) Submit specimen in an ARUP Standard Transport Tube.
Remarks: Indicate source on test request form. CSF is the only acceptable specimen type.
Unacceptable Conditions: Heat-inactivated or contaminated specimens.
Stability (collection to initiation of testing): Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
Interpretive Data:
Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a nontype-specific screening test.
Please refer to Statement E in the Compliance Statements section in the front of the Laboratory Test Directory.