ARUP's Laboratory Test Directory
| 0050294: Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA (HerpeSelect®) |
| Test Mnemonic: HERP II | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 0.5 mL serum at 2-8°C. (Min: 0.2 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.1 mL serum at 2-8°C. Unacceptable Conditions: Severely lipemic, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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0.89 IV or less: Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G. 0.90-1.10 IV: Equivocal - Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-14 days may be helpful. 1.11 IV or greater: Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection. |
| Interpretive Data: | |
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Individuals infected with HSV may not exhibit detectable IgG antibody to glycoprotein G in the early stages of infection and 5-10% of infections may occur with glycoprotein G-deficient virus. Detection of antibody presence in these cases may only be possible using a nontype-specific screening test.
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| CPT Code(s): | |
| 86696 |