ARUP's Laboratory Test Directory

0050245: Epstein-Barr Virus Antibody to Nuclear Antigen, IgG

Test Mnemonic: EBV NA
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Tue-Sat

Reported: Within 24 hours

Specimen Required:  
Collect: One 4 mL SST.

Transport: 0.5 mL serum at 2-8°C. (Min: 0.2 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.1 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent."

Unacceptable Conditions: Contaminated or heat-inactivated specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
0.90 IV or less: Negative - No significant level of detectable IgG antibody to EBV nuclear antigen.
0.91-0.99 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.00 IV or greater: Positive - IgG antibody to EBV nuclear antigen detected, which may indicate a current or past EBV infection.

Note:
EBNA values obtained with different manufacturers' assay methods may not be used interchangeably.  The magnitude of the reported EBNA level cannot be correlated to an endpoint titer.

CPT Code(s):
86664