ARUP's Laboratory Test Directory

Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM : 0050240

Mnemonic: EBV M

Ordering Recommendation: Aids in the diagnosis of primary Epstein-Barr virus infectious mononucleosis, in conjunction with other serologic tests. Not a stand-alone test.
Methodology: Semi-Quantitative Chemiluminescent Immunoassay
Performed: Mon-Sun
Reported: 1-2 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Tissue or urine. Contaminated or heat-inactivated specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
Effective February 19, 2013

35.9 U/mL or less: Not Detected
36.0-43.9 U/mL: Intermediate.  Repeat testing in 10-14 days may be helpful.
44.0 U/mL or greater: Detected
Interpretive Data: Interpretive information regarding serologic features of EBV-associated diseases is available at www.arupconsult.com/ebvdx.
Note: EBV IgM values obtained with different manufacturers' assay methods may not be used interchangeably.  The magnitude of the reported EBV IgM level cannot be correlated to an endpoint titer.
CPT Code(s): 86665
Cross References: EBV Antibody to Viral Capsid Antigen (Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM), EBV VCA (Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM), Infectious Mononucleosis (Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM)