ARUP's Laboratory Test Directory

Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG : 0050225

Mnemonic: EBV EAD

Methodology: Semi-Quantitative Chemiluminescent Immunoassay
Performed: Mon-Sun
Reported: 1-2 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimen plainly as "acute" or "convalescent." Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Urine. Contaminated or heat-inactivated specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
8.9 U/mL or less: Negative - No significant level of detectable IgG antibody to EBV early (D) antigen.
9.0-10.9 U/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
11.0 U/mL or greater: Positive - IgG antibody to EBV early (D) antigen detected, which may indicate a current or past EBV infection.
Note: EBV EA-D values obtained with different manufacturers' assay methods may not be used interchangeably.  The magnitude of the reported EBV EA-D level cannot be correlated to an endpoint titer.
CPT Code(s): 86663
Cross References: EBNA Antibody (Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG), EBV Antibody to Early D Antigen (Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG), EBV Nuclear Antibody (Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG), Infectious Mononucleosis (Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG)
 
 

 

 

 
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