#ExistRefRangeSet>
Reference Interval:
#ExistRefRange>Effective August 20, 2012
*ExistRefRange>
#ExistRefRangeTable> | Test Number
| Components
| Reference Interval
| | | Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA
| None Detected.
| | 2002693
| Double-Stranded DNA (dsDNA) Antibody, IgG by IFA (using Crithidia luciliae)
| Less than 1:10
|
*ExistRefRangeTable>
|
*ExistRefRangeSet>
#ExistInterpDataSet>
| Interpretive Data: |
#ExistInterpData>Positivity for anti-double stranded DNA (anti-dsDNA) IgG antibody is a diagnostic criterion of systemic lupus erythematosus (SLE). Specimens are initially screened by enzyme-linked immunosorbent test (ELISA). All ELISA results reported as "detected" (positive) are confirmed by a highly specific IFA titer (Crithidia luciliae indirect fluorescent test [CLIFT]). Some patients with early or inactive SLE may be positive for anti-dsDNA IgG by ELISA but negative by CLIFT. If the patient is negative by CLIFT but positive by ELISA and clinical suspicion remains, consider antinuclear antibody (ANA) testing by IFA. Additional information and recommendations for testing may be found at http://www.arupconsult.com/Topics/AutoimmuneDz/ConnectiveTissueDz/index.html.
*ExistInterpData>
|
*ExistInterpDataSet>
#ExistNote>
| Note: |
If dsDNA IgG antibody is detected, the result will be confirmed by Double-Stranded DNA (dsDNA) Antibody, IgG by IFA (using Crithidia luciliae). Additional charges apply.
|
*ExistNote>
#ExistCPT>
| CPT Code(s): |
86225; if reflexed, add 86256
|
*ExistCPT>
#ExistCrossReferences>
Cross References: |
Anti-dsDNA Antibody (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
, Anti-Native DNA (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
, Crithidia luciliae (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
, DNA Double Stranded Antibody (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
, DNA IgG (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
, Drug Induced SLE (Double-Stranded DNA (dsDNA) Antibody, IgG by ELISA with Reflex to dsDNA Antibody, IgG by IFA)
|
*ExistCrossReferences>