Reference Interval:
None detected.
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| Interpretive Data: |
dsDNA antibodies are screened using an ELISA assay. Positive results are titered by IFA. "None detected" correlates with an IFA titer of less than 1:10.
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| Note: |
dsDNA antibodies (1:10 or greater) are found in 50-60% of systemic lupus erythematosus (SLE), 20-30% in Sjögren syndrome, 20-25% in mixed connective tissue disease (MCTD), and less than 5% in progressive systemic sclerosis (PSS). High titers of antibody to native (double stranded) DNA are specific for SLE.
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| CPT Code(s): |
86225
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