ARUP's Laboratory Test Directory

IA-2 Antibody : 0050202

Mnemonic: IA-2

Ordering Recommendation: Not recommended in routine evaluation or management of diabetes mellitus (DM). Glutamic Acid Decarboxylase Antibody (GAD) (2001771) and IA-2 Antibody (insulinoma antigen 2) recommended for initial screening of suspected cases of type 1 DM.
Methodology: Quantitative Radioimmunoassay
Performed: Fri
Reported: 2-10 days
Specimen Required: Collect: Serum separator tube or plain red.

Specimen Preparation: Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma. Hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 months
Reference Interval:
0.0-0.8 Kronus Units/mL
Interpretive Data: A value greater than 0.8 Kronus Units/mL is considered positive for IA-2 Antibodies.
Kronus Units are arbitrary. Kronus Units = U/mL
CPT Code(s): 86341
Cross References: Beta-Cell Autoantibody to IA-2 (IA-2 Antibody), Insulinoma Associated 2 Antibody (IA-2 Antibody), Islet Cell Antigen (ICA) 512 (IA-2 Antibody)