ARUP's Laboratory Test Directory
| 0050183: Coccidioides Antibody by ID |
| Test Mnemonic: COCCI-PPT | |
|
Methodology: Immunodiffusion
Performed: Sun-Fri Reported: 2-4 days |
| Specimen Required: | |
|
Collect: One 4 mL SST or 2 mL CSF.
Transport: 0.5 mL of serum or CSF at 2-8°C. Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL of serum or CSF at 2-8°C. Unacceptable Conditions: Grossly hemolyzed or bloody specimens. Stability: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
|
| Reference Interval: |
| None detected. |
| Interpretive Data: | |
|
For Coccidioides, immunodiffusion measures IgM and a positive result may suggest active or recent infection. Serum precipitins may be detected within one to three weeks after the onset of primary infection, but are rarely detected six months after infection. Precipitins may reappear with relapse or persist in disseminated cases. IgG antibody may also be demonstrated by a band in immunodiffusion distinct from the IgM precipitin band. Negative fungal serology does not rule out the possibility of current infection.
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| Note: | |
| This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens. |
| CPT Code(s): | |
| 86635 |