ARUP's Laboratory Test Directory
| 0050179: Coccidioides Antibody, IgG by ELISA |
| Test Mnemonic: COCCI G | |
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#ExistMethodology>
Methodology: Enzyme-Linked Immunosorbent Assay
*ExistMethodology> #ExistPerformed> Performed: Mon-Fri *ExistPerformed> #ExistReported> Reported: 1-5 days *ExistReported> |
| Specimen Required: | |
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#ExistCollect>
Collect: One 4 mL SST or 2 mL CSF.
*ExistCollect> #ExistTransport> Transport: 1 mL serum or CSF at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistPedCollectTransport> Pediatric Collection/Transport: 0.15 mL serum or CSF at 2-8°C. *ExistPedCollectTransport> #ExistConditions> Unacceptable Conditions: Severely lipemic, contaminated, or hemolyzed specimens. *ExistConditions> #ExistStability> Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) *ExistStability> |
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| Reference Interval: |
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#ExistRefRange> 0.9 IV or less: Negative- No significant level of Coccidioides IgG antibody detected. 1.0-1.4 IV: Equivocal - Questionable presence of Coccidioides IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1.5 IV or greater: Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection. *ExistRefRange> |
| Interpretive Data: | |
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#ExistInterpData>
IgG antibodies usually appear by the third week of infection and may persist for years. Both tube precipitin (TP) and CF antigens are represented in the ELISA tests.
*ExistInterpData> |
| Note: | |
| Negative fungal serology does not rule out the possibility of current infection. |
| CPT Code(s): | |
| 86635 |