ARUP's Laboratory Test Directory

Histoplasma Antibody by ID : 0050174

Mnemonic: HISTO PPT

Methodology: Qualitative Immunodiffusion
Performed: Sun-Fri
Reported: 2-4 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min 0.1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Body fluids.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
None detected.
Interpretive Data: The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H). The M band often appears first and may occur without the H band. M precipitin is found in about 70 percent of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10 percent of patients.
Note: Negative fungal serology does not rule out the possibility of current infection.
CPT Code(s): 86698
Cross References: Histoplasma Precipitin (Histoplasma Antibody by ID)