ARUP's Laboratory Test Directory

Varicella-Zoster Virus Antibody, IgG : 0050167

Mnemonic: VZE

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue-Sat
Reported: Within 24 hours
Specimen Required: Collect:  One 4 mL serum separator tube.

Storage/Transport Temperature:  1 mL serum at 2-8°C. (Min: 0.1 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent."

Unacceptable Conditions:  Icteric, contaminated, heat-inactivated, or hemolyzed specimens.

Stability (collection to initiation of testing):  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
0.89 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. Positive IgG antibody levels in the absence of current clinical symptoms may indicate immunity (98% correlation with IFA).
Interpretive Data: The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
CPT Code(s): 86787
Cross References: VZV Antibody, IgG
 
 

 

 

 
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