ARUP's Laboratory Test Directory
| 0050167: Varicella-Zoster Virus Antibody, IgG |
| Test Mnemonic: VZE | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue-Sat Reported: Within 24 hours |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.3 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.1 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent." Unacceptable Conditions: Icteric, contaminated, heat-inactivated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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0.89 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody. 0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. Positive IgG antibody levels in the absence of current clinical symptoms may indicate immunity (98% correlation with IFA). |
| Interpretive Data: | |
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The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
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| CPT Code(s): | |
| 86787 |