ARUP's Laboratory Test Directory

0050162: Varicella-Zoster Virus Antibodies, IgG & IgM

Test Mnemonic: VZV PAN
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun-Sat

Reported: 1-5 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.2 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.  Please mark specimen plainly as "acute" or "convalescent."

Unacceptable Conditions: See individual components.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
 
Test Number Components Reference Interval
0050167Varicella-Zoster Virus Antibody, IgG 0.89 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
0.90-1.09 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. Positive IgG antibody levels in the absence of current clinical symptoms may indicate immunity (98% correlation with IFA).
0099314Varicella-Zoster Virus Antibody, IgM 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

CPT Code(s):
86787 VZ IgG; 86787 VZ IgM

 

 

 
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