ARUP's Laboratory Test Directory

Varicella-Zoster Virus Antibodies, IgG and IgM : 0050162

Mnemonic: VZV PAN

Methodology: Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay
Performed: Sun-Sat
Reported: 1-5 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: See individual components.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
 
Test Number Components Reference Interval
0050167Varicella-Zoster Virus Antibody, IgG Effective August 20, 2012

134 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
135-165 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
166 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.
0099314Varicella-Zoster Virus Antibody, IgM 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

CPT Code(s): 86787 x2
Cross References: VZV Antibodies, IgG & IgM