Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.
Storage/Transport Temperature: Refrigerated.
Unacceptable Conditions: Contaminated or severely lipemic specimens.
Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
< 1:8
Interpretive Data:
Less than 40 percent of patients have positive tests when active disease is present. Frequent cross-reactions occur in patients with histoplasmosis or coccidioidomycosis. Paired sera may detect rise in titer to single antigen.
Note:
Negative fungal serology does not rule out the possibility of current infection.
