ARUP's Laboratory Test Directory
| 0049378: CHOP Gene Rearrangement by FISH |
| Test Mnemonic: CHOPFISH | |
|
Methodology: Fluorescence in situ Hybridization
Performed: Thu-Fri Reported: 4-12 days |
| Specimen Required: | |
|
Collect: Tumor tissue
Transport: Paraffin-embedded, formalin-fixed tissue block at 20-25°C. Protect paraffin block from excessive heat. Ship in cooled container during summer months. Include surgical pathology report. Also acceptable: 6 tissue sections (from formalin-fixed, paraffin-embedded tissue block) on 6 "positively charged" or "plus" slides. Unacceptable Conditions: No tumor in tissue. Frozen samples and samples fixed/processed in alternative fixatives (alcohol, Prefer®). Stability: Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable |
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| Reference Interval: |
| By report. |
| Interpretive Data: | |
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This assay indicates translocation has occured, but not the specific translocation partener. Approximately 95% of all translocations involve the translocation partner on chromosome 16. The remaining 3-6% have chromosome 22 as the translocation partner.
Please refer to Statement A in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 88368 x2 |