ARUP's Laboratory Test Directory

Mismatch Repair by IHC : 0049302

Mnemonic: MSI

Methodology: Qualitative Immunohistochemistry
Performed: Mon, Thu
Reported: Within 5 days
Specimen Required: Collect: Tumor tissue from colon carcinoma.

Specimen Preparation: Formalin fix (10% neutral buffered formalin is preferred) and paraffin embed specimen. If sending precut slides, do not oven bake. Transport tissue block or 15 five micron unstained slides. (Min: 12 slides) Protect paraffin block and/or slides from excessive heat.

Storage/Transport Temperature: Room temperature or refrigerated. Ship in cooled container during summer months

Remarks: Only tissue that is clearly carcinoma (established by histological criteria) should be tested. Include surgical pathology report.

Unacceptable Conditions: Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Depleted or no tumor in tissue. Depleted specimens. Specimens submitted with non-representative tissue type.

Stability (collection to initiation of testing): Paraffin block: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Interpretive Data: Refer to report

Refer to Statement B under Testing Information at http://www.aruplab.com.
CPT Code(s): 88342 x4
Cross References: HNPCC/Lynch Syndrome (Mismatch Repair by Immunohistochemistry), Lynch Syndrome/Microsatellite Instability (Mismatch Repair by Immunohistochemistry), MSI (Mismatch Repair by Immunohistochemistry)
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org