ARUP's Laboratory Test Directory

0049270: Ki-67 Tissue Assay, Paraffin

Test Mnemonic: KI67 IP
Methodology: Immunohistochemistry

Performed: Mon-Fri

Reported: Within 5 days

Specimen Required:  
Collect: Tumor tissue.

Transport: Paraffin-embedded, formalin-fixed tissue block enriched with tumor at 20-25°C.  Protect paraffin block from excessive heat.  Ship in cooled container during summer months. Include surgical pathology report.

Unacceptable Conditions: Paraffin block with no tumor tissue remaining; samples fixed in B-5 or Bouin's fixative.

Stability: Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable

Interpretive Data:
The Ki-67 antigen is used to estimate the growth fraction of a tumor cell population.  In many malignancies, a high Ki-67 value generally correlates with an aggressive behavior. Results of this test should be interpreted with caution on the context of other data.
Assay is performed on paraffin-embedded, formalin-fixed tissue.  Antibody clone is MIB-1 and the detection system is LSAB.

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.



CPT Code(s):
88360