ARUP's Laboratory Test Directory

EGFR by FISH : 0049234

Mnemonic: EGFRFISH

Methodology: Fluorescence in situ Hybridization
Performed: Weekly
Reported: 4-12 days
Specimen Required: Collect:  Tumor tissue.

Transport:  One paraffin-embedded, formalin-fixed tissue block at 20-25°C.  Protect paraffin block from excessive heat.  Ship in cooled container during summer months.  Include surgical pathology report.

Remarks:  Only tissue that is clearly carcinoma (established by histopathologic criteria) should be tested.

Unacceptable Conditions:  Samples fixed/processed in alternate fixatives (alcohol, Prefer®, etc.) should not be submitted.  No tumor in tissue or frozen tissue.

Stability:  Paraffin block: Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable
Reference Interval:
 
Test Number Components Reference Interval
 EGFR by FISH Nonamplified: LSI EGFR:CEP7 Less than 2.0
Amplified: LSI EGFR:CEP7 Greater than or equal to 2.0
 EGFR:CEP7 By report
 EGFR per Cells Counted Ratio By report

CPT Code(s): 88368 x2
 
 

 

 

 
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