ARUP's Laboratory Test Directory
| 0049220: Cathepsin D, Paraffin |
| Test Mnemonic: CATH IP | |
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Methodology: Immunohistochemistry
Performed: Mon-Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: Tumor tissue.
Transport: Paraffin-embedded, formalin-fixed tissue block enriched with tumor at 20-25°C. Include surgical pathology report. Protect paraffin block from excessive heat; ship in a cooled container during summer months. Unacceptable Conditions: Paraffin block with no tumor tissue remaining. Samples fixed in formalin substitute. Stability: Paraffin block: Ambient: Indefinitely; Refrigerated: Acceptable; Frozen: Unacceptable |
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| Reference Interval: |
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Not established Report includes: Cathepsin D in tumor cells and Cathepsin D in stromal cells |
| Interpretive Data: | |
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Assay is performed on paraffin-embedded, formalin-fixed tissue. Antibody is polyclonal and the detection system is labeled streptavidin biotin (LSAB). Staining of greater than 5% indicates a positive result and has been associated in some studies with an improved prognosis. Results of this test should be interpreted with caution in the context of other data. Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 88360 |