Reference Interval:
Negative
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| Interpretive Data: |
The anti-GBM IFA methodology has been shown to be less specific than the quantitative tests for circulating antibodies such as the Multi-Analyte Fluorescent Detection (MAFD). The antibody used in this assay, although directed to human IgG F(ab')2, can bind to light chain sites common to all immunoglobulins causing it to be more sensitive but less specific. The determination of a positive result is based upon a diffuse "linear" staining pattern as viewed through a fluorescent microscope, all positive results should be confirmed by quantitative tests and/or renal biopsy.
Refer to Statement B under Testing Information at http://www.aruplab.com.
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| CPT Code(s): |
86255
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Cross References: |
Anti-GBM Antibody (Glomerular Basement Membrane Antibody, IgA (IFA)), Anti-Glomerular Basement Membrane Antibody (Glomerular Basement Membrane Antibody, IgA (IFA)), Goodpasture's Syndrome (Glomerular Basement Membrane Antibody, IgA (IFA)) |