ARUP's Laboratory Test Directory
| 0049015: Osmotic Fragility, Erythrocyte |
| Test Mnemonic: OSM FRAG | |
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Methodology: Spectrophotometry
Performed: Mon-Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: One 5 mL green (sodium or lithium heparin).
Transport: 5 mL whole blood and two unfixed smears. Transport at 20-25°C. Send Sunday-Thursday only. Pediatric Collection/Transport: 1 mL whole blood and two unfixed smears. Transport at 20-25°C. Send Sunday-Thursday only. Remarks: Samples must be received within 24 hours of collection; testing must be performed within 48 hours of collection. Unacceptable Conditions: Hemolyzed blood. Stability: Ambient: 24 hours |
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| Reference Interval: |
| Within normal curve limits. A graph will accompany laboratory report. |
| Interpretive Data: | |
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For patients with acute hemolysis, a normal red cell osmotic fragility test result cannot exclude an osmotic fragility abnormality since the osmotically labile cells may be hemolyzed and not present. Recommend testing during a state of prolonged homeostasis with stable hematocrit.
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| CPT Code(s): | |
| 85555 |