ARUP's Laboratory Test Directory

KRAS Mutation Detection : 0040248

Mnemonic: KRAS

Methodology: Polymerase Chain Reaction/Pyrosequencing
Performed: Sun-Sat
Reported: 10-12 days
Specimen Required: Collect: Tumor tissue.

Specimen Preparation: Formalin fix and paraffin embed tissue. Protect from excessive heat. Transport tissue block or 5 unstained 5 micron slides. (Min: 3 slides).

Storage/Transport Temperature: Room temperature. Ship in cooled container during summer months.

Remarks: Include surgical pathology report.

Unacceptable Conditions: No tumor in tissue. Specimens fixed/processed in alternative fixatives (alcohol, Prefer®). Frozen specimens.

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Interpretive Data: Refer to report.

Refer to Statement B under Testing Information at http://www.aruplab.com.
Note: This assay detects mutations in codons 12, 13, and 61.
CPT Code(s): 88381 Microdissection; 83907 Lysis; 83898 x2 Amplification; 83904 x2 Sequencing; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test oncologic or inherited disorders.
Cross References: Cetuximab (Erbitux) (KRAS Mutation Detection) , Panitumumab (Vectibix) (KRAS Mutation Detection)
 
 

 

 

 
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