ARUP's Laboratory Test Directory

NPM1 Mutation by PCR and Fragment Analysis : 0040174
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Additional Technical Information
  


Mnemonic: NPM1-F

Methodology: Polymerase Chain Reaction/Fragment Analysis
Performed: Varies
Reported: 5-7 days
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA) OR tissue.

Specimen Preparation: Whole blood: Transport 5 mL. (Min: 1 mL) OR Bone marrow: Transport 3 mL. (Min: 1 mL) OR FFPE tumor tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport tissue block or four 10-micron shavings. Tissue block will be returned after testing. Transport block(s) and/or shavings in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.

Storage/Transport Temperature: Whole blood OR Bone marrow: Refrigerated. FFPE tumor tissue: Room temperature or refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions: Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue: Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.

Stability (collection to initiation of testing): Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable

Interpretive Data: Refer to report

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 81310, G0452