ARUP's Laboratory Test Directory

SYT-SSX t(X;18) Translocations by RT-PCR : 0040114
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Additional Technical Information
  


Mnemonic: SYT-SSX

Methodology: Reverse Transcription Polymerase Chain Reaction/Fluorescence Monitoring
Performed: RNA Isolation: Sun-Sat; Assay: Varies
Reported: 4-7 days
Specimen Required: Collect: Tumor tissue.

Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport four 10-micron shavings. Also acceptable: Tissue block; will be returned after testing. Transport block(s) and/or shavings in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.

Storage/Transport Temperature: Room temperature or refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions: No tumor in tissue. Specimens fixed/processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives. Decalcified specimens. Tissue on slides.

Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Refer to report.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

See Compliance Statement B: www.aruplab.com/CS
Note: A positive result indicates the presence of a t(X;18) chromosomal translocation. A negative result does not entirely exclude the presence of a t(X;18) chromosomal translocation.
CPT Code(s): 81479, G0452
Cross References: Synovial Sarcoma (SYT-SSX t(X;18) Translocations by RT-PCR), X;18 (SYT-SSX t(X;18) Translocations by RT-PCR)