ARUP's Laboratory Test Directory

APC Resistance Profile with Reflex to Factor V Leiden : 0030192

Mnemonic: APC R

Methodology: Clotting/Polymerase Chain Reaction/Fluorescence Monitoring
Performed: Refer to individual components
Reported: 1-5 days
Specimen Required: Collect:  One 5 mL lt. blue (sodium citrate) and one 5 mL lavender (EDTA).

Transport:  1.5 mL platelet-poor plasma, frozen and one 5 mL whole blood (EDTA) at 2-8°C.  Do not freeze whole blood. (Min: 1 mL of each)

Unacceptable Conditions:  Serum. Severely hemolyzed specimens. Nonfrozen specimens for APC.

Stability:  APC - Ambient: 2 hours; Refrigerated: 4 hours; Frozen: 2 weeks
FACV - Ambient: 3 days; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval:
 
Test Number Components Reference Interval
 APC Resistance Profile Greater than 0.61
 Factor V Leiden by PCR & Fluorescence Monitoring Negative: The sample is negative for factor V Leiden, R506Q mutation.

Note: If APC resistance is normal, no further testing will be performed.  If APC resistance is low, then Factor V Leiden by PCR will be added.  Additional charges may apply.
CPT Code(s): 85307 APC; if reflexed, add 83890 Isolation; 83898 Amplification; 83912 Interpretation and report; 83896 Nucleic acid probes - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
 
 

 

 

 
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